Organic 314 Chemistry Labs

Week 1:  Molecular modeling and Safety:  Go over MM, Safety and prepare ethanol sample
    SAFETY:   Safety Link, Click  "view online" or order the book to answer the questions in the safety quiz below
                                                        Safety Quiz               due at the beginning of your next lab (week of Sept 8), hand in bubble sheet
                                                        How to interpret a MSDS
                                                        Distillation Prelab      due at the beginning of your next lab (week of Sept 15), hand in bubble sheet
    MOLECULAR MODELING:      MM worksheet        due by Friday, Sept 12, in class.

Week 2:  No lab  Memorial Day

Week 3:   Theory of Distillation - meet in prelab room 
                Start Fermentation   - Bring distillation lab report                                                          Safety Quiz Due at the beginning of  prelab
                DVD:  Distilleries

Week 4:  Fractional Distillation                                                                                                     Distillation Prelab Due at the beginning of  prelab
               Procedure:  To be handed out - meet in prelab room first                                               MM Worksheet Due by Friday, Sept 12.
               Distillation Lab Report    Due before leaving
               Mass Spectroscopy Prelab     due at the beginning of your next lab

Week 5:  Dry lab:  UNMC trip
              Limits of Molecular Modeling - Use Spartan '06                          Due Oct 3          use time wisely this week!
              Stereochemistry   Molecular Modeling use Spartan '06                Due Oct 16

Week 6:  Mass Spectroscopy:  Turn in MS-Prelab.  Dry lab - to be done during lab.
              Steam Distillation Prelab    due at the beginning of next lab
               Cinnamic Acids essay for the prelab.

Week 7:  Steam Distillation of Cloves
                Procedure:  To be handed out                                                    Steam Distillation Prelab Due
                Lab Report:  Report due at start of next lab
                                                                                                                  Limits of Molecular Modeling Due Oct 3
                                                                                                                  Stereochemistry Due Oct 16
               Chromatography/Extraction Prelab - bring to prelab, to be completed during prelab, collected at the end of prelab

Week 8   Column Chromatography;  extraction of chlorophyll and B-carotene
               Lab report - 2 week lab report, due in two weeks
        
Week 9  Thin Layer chromatography:  TLC, and IR Analysis.
                J. chem Ed. article - read
                Lab report - same as last weeks

Week 10  Two Week Extraction, Chromatography, GC/MS and IR data

                Procedure:  Due to Dr. Peitz well before the start of week 12 lab
                Your Final Lab report for this lab:  Due before the end of the semseter
                Explosives   An application of Molecular Modeling.  Use Spartan '06   Due Nov 25 before break.

Week 11   Polarimetry and IR  Lab
               Polarimetry Prelab
               Procedure:  to be handed out, bring prelab and report to lab
               Lab Report:  Report due before you leave

Week 12  Conduct week 10 lab that you designed and had verified by Dr. Peitz

Week 13  Mid term Break
Week 14  Fall Break
Week 15  ACS

Week 12  Eugenol SN2 reaction
                Procedure
                Lab report, GC/MS, class variations, IR
                Microbiology data analysis







Organic 315 Chemistry Labs
Just like the VCR destroyed the movie industry, the audio tape destroyed
 the music industry, and the photocopier destroyed the print industry...

Week 1:  In Class Safety Review
            Crystallization Prelab
            Melting Point Prelab
            Handout for prelabs

Week 2  Crystallization of Triphenylmethanol, melting point determination
            Lab Procedure
            Lab Report 
            Prelab for Ester Synthesis

Week 3   Synthesis:  Esterification of Eugenol
            Lab Procedure
            Lab Report to include IR and GC/MS - Example lab report - available only after you have turned in your report.  

Week 4    Esterification of eugenol, Pt. 2
                Prelab:  Molecular Modeling for Diels Alder

Week 5  Diels Alder
            Lab Procedure
            
Week 6 Diels Alder, Pt. 2 and  13C NMR dry lab
               Work on lab report Lab Report to include IR and GC/MS
               Prelab  Molecular Modeling for Hydrolysis               

Week 7  In Lab:  Hydrolysis
            Lab Procedure
            Lab Report to include IR and GC/MS

Week 8  Hydrolysis Pt. 2 and  1H NMR dry lab
            Work on lab report Lab Report to include IR and GC/MS           
            Prelab: Molecular Modeling for FC

Week 9  In Lab Friedel Crafts
    Use the following literature in your G: drive course_materials  2008_spring_che_031501_organic_chemistry_ii  or che_031502 folder
     to help in the development of a full and complete procedure for the Friedel-Crafts alkylation of Eugenol.  Your text is good too.
        1.  An AlCl3 Procedure using a different chloride and arene, but similar overall: with-AlCl3.pdf
        2.  The idea: Student-Designed Experimental Procedure:  Student-inquiry.pdf
        3.  Wikipedia:  http://en.wikipedia.org/wiki/Friedel-Crafts_reaction
        4.  Some MS analysis ideas:  GC-MS.pdf

    Want to try an acceptable, alternate, green procedure?  use the following papers on the G: drive
        5.  green.pdf
        6.  green2.pdf

Week 10  FC, Pt. 2

    Lab Report to include IR and GC/MS analysis.